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Tremella(Tremella fuciformis)

Below the products: Tremella guide

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Tremella Powders · LONGEVITY, Aloha Fungi product packaging
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Tremella

Tremella fuciformis

Powders · LONGEVITY

249 zł

Tremella guide

Version 2.0 · Updated: 24 August 2026 · Subject-matter reviewer: Mateusz Rosa, founder of Aloha Fungi, TCM therapist, Doctor of Acupuncture (WFAS), author of books on functional mushroom supplementation.

  • Tremella fuciformis, in Polish trzęsak morszczynowaty, Chinese yin er (银耳, „silver ear"), bai mu er (白木耳, „white tree ear"), xue er (雪耳, „snow ear"), Japanese shiro kikurage. English names: snow fungus, silver ear, white jelly mushroom.
  • The raw-material literature describes TFPS polysaccharides, including glucuronoxylomannan, as well as β-1,3/1,6-glucans, uridine, mannitol and ergosterol. The presence and quantity of compounds in a product depend on the raw material, process and specific batch.
  • The literature describes the physicochemical properties of TFPS and cell or animal studies involving NGF, CREB, Dectin-1 and TLR4 pathways. These models cannot automatically be translated into an effect of a supplement in humans.
  • Two small randomised studies concerned specific preparations and selected participant groups: Ban 2018 (n=75) and Gitsomboon 2024 (n=56). They do not establish an effect for every Tremella extract or a cosmetic result from the Aloha Fungi product.
  • In TCM, Tremella is historically classified as a Lung and Stomach Yin tonic. This is a description of tradition, not a modern medical indication or a promise of an outcome.
  • Check the current form, ingredients and serving of the Aloha Fungi product on the label for the specific variant. Any laboratory document should match the batch number on the pack.

What tremella is and where it comes from

Tremella is the common name for the mushroom Tremella fuciformis of the Tremellaceae family. The Polish name trzęsak morszczynowaty refers to the resemblance of the branching lobes of the fruiting body to bladderwrack fronds. Chinese yin er (银耳, „silver ear"), Japanese shiro kikurage, English snow fungus, silver ear and white jelly mushroom describe the same lacy, gelatinous structure.

It is a parasitic mushroom growing mainly in the tropical and subtropical zones. In the wild it does not develop directly on wood but as a parasite of other wood-rotting fungi, most often of the genus Annulohypoxylon. The fruiting body has a characteristic lacy, gelatinous structure, translucent and white to yellowish when fresh, hard and pale yellow when dried.

In controlled cultivation Tremella is grown together with its host fungus. Parameters for a specific raw material, including polysaccharide content and contaminant test results, should come from the documentation for that batch.

Tradition of use

The first written mentions of yin er appear in Chinese medical texts from the Tang dynasty (618-907 CE). It was traditionally an imperial mushroom reserved for the court, called „plant caviar". The most famous cosmetic consumer of Tremella in Chinese history was the concubine Yang Guifei (719-756 CE) at the court of Emperor Xuanzong, who, according to the records, ate a yin er dessert daily to maintain her beauty.

In the classic work Ben Cao Gang Mu (1578), Li Shizhen placed Tremella within traditional descriptions of Lung and Stomach Yin and Jin Ye. We include this classification as historical context, not as an indication for a modern supplement.

The modern renaissance of Tremella in the West began in the 1990s, when Japanese and Korean cosmetics manufacturers started using TFPS polysaccharides as a plant alternative to animal-derived hyaluronic acid.

Bioactive composition, what is in the extract

The main complex described in the literature is the TFPS polysaccharides. Structurally they include glucuronoxylomannan, a linear (1→3)-α-D-mannose chain with side branches of β-D-xylose, α-D-fucose and β-D-glucuronic acid. Published parameters of research material are not automatically parameters of a product.

β-1,3/1,6-glucans occur within the TFPS fraction and as a separate component. Their relationships with Dectin-1 and TLR4 receptors are subjects of laboratory research.

Composition analyses have also described uridine, mannitol, ergosterol, provitamin D₂, amino acids and trace elements. The presence and quantity of individual compounds depend on the raw material and analytical method.

Chemical analyses have shown that the polysaccharide fraction of T. fuciformis contains up to 87.76% of a structural counterpart of hyaluronic acid with a molecular weight above 2000 kDa. This is not the same compound, however. The similarity concerns the humectant function, not chemical identity.

A fruiting-body extract and mycelium grown on grain are different raw materials. When comparing products, check the part of the mushroom, carriers, extraction method, declared standardisation and documentation for the specific batch.

What researchers have studied: three areas

Area 1. Water-binding properties of TFPS

The structure of glucuronoxylomannan makes TFPS relevant to research on water-binding materials. Wu 2019 describes in-vitro data on the molecular weight and behaviour of these polysaccharides. It is not a study of an oral supplement or proof of a visible skin change in humans.

Wen 2016 concerns an animal model, while Hu 2021 concerns fibroblasts exposed to UVA. The authors reported changes in selected laboratory markers. These findings do not establish a cosmetic result for a person taking the Aloha Fungi product.

Area 2. NGF, CREB and the cholinergic system

Park 2007 concerns PC12h cells, while Park 2012 uses a rat model. The papers describe neurites, CREB transcription and ChAT expression in those models. They are not evidence of a cognitive effect from a supplement in humans.

Ban 2018 was a small randomised study involving 75 people with subjective memory complaints. It concerned a specific preparation and population, not the Aloha Fungi product. The result needs replication and does not justify recommending Tremella for a memory-related goal.

Area 3. β-glucans and laboratory models

Tremella β-glucans have been studied in laboratory models involving PI3K/Akt, adipogenesis genes and the microbiota. These are directions of mechanistic research, not a claim of a health outcome or a reason to change treatment.

Dectin-1, TLR4, Treg, IL-1β and TNF-α are markers used in preclinical research. The presence of such a mechanism in a paper does not tell us what outcome a person will experience after consuming a specific supplement.

What tremella does not do

Tremella does not cure Alzheimer’s disease, dementia or other neurodegenerative diseases and does not replace antidiabetic medicines. A result from one trial of a specific preparation cannot be transferred to every supplement. Tremella also does not replace hyaluronic acid in a cosmetic. They are different chemical compounds. There are no clinical trials with measured skin parameters confirming that oral Tremella reverses wrinkles.

How to use Tremella

Use the serving on the label for the specific variant

Different forms and batches may have different instructions. Use the serving and preparation method on the current product label. Do not convert quantities from scientific studies into Aloha Fungi capsules, drops or powder yourself.

Do not exceed the recommended daily serving. If the label and the website differ, pause use and ask customer service to confirm the current instruction.

How to serve it

If the label for the relevant form allows it, Tremella can be added to warm water, tea, cacao, a plant drink, smoothie, soup or oatmeal. Traditional culinary pairings include jujube, goji, lily and lotus seeds.

There are no reliable data establishing a universal schedule of use or a time to an expected result. Regularity does not replace label instructions and an individual safety assessment.

How to assess tolerance

Do not treat skin appearance, wellbeing or a single measurement as proof that the product works. Such observations are affected by many other factors.

If an unwanted symptom appears, stop use and discuss the next step with a doctor or pharmacist. The safety section below covers situations that need particular care.

Combining Tremella with other mushrooms

Tremella + Lion’s Mane

Both mushrooms appear in literature on different NGF models, but no clinical study establishes synergy from combining them or an advantage over using them separately.

Pair with:Lion’s Mane

Tremella + Reishi

TCM sources sometimes describe both raw materials in the Yin-tonic category. This is traditional context, not clinical confirmation of a combined effect or an indication for use.

Pair with:Reishi

Tremella + Cordyceps

Traditional sources place these raw materials on opposite sides of the Yin and Yang description. This is not evidence of homeostasis or a confirmed health outcome for athletes or any other group.

Pair with:Cordyceps

Tremella + Chaga or Coriolus

No clinical studies establish a particular benefit from these combinations. Using several supplements also makes it harder to attribute tolerance or an unwanted symptom to one ingredient.

Pair with:ChagaCoriolus

How does TCM describe Tremella?

In classical Chinese Materia Medica, Tremella, yin er, is classified as a Yin tonic and associated with descriptions of the Lung, Stomach and Jin Ye. These are historical categories within a traditional system.

This is a cultural framework, not a medical diagnosis or evidence that the product is effective. Concepts such as Yin, Jin Ye or meridian do not correspond one to one with Western anatomy or physiology.

Tastesweet, bland (淡 dàn)
Natureneutral (some sources: slightly cooling)
MeridiansLung, Stomach, Kidney
CategoryYin tonic (滋阴药 zī yīn yào)

Contraindications and interactions

Absolute contraindications

Known allergy to mushrooms of the Tremellaceae family or cross-hypersensitivity to other medicinal mushrooms (symptoms: itching, swelling, skin redness, cough, shortness of breath).

Status after organ transplant with active immunosuppression (cyclosporine, tacrolimus, mycophenolate, everolimus). β-glucans activate Dectin-1 and TLR4, which could theoretically weaken the effect of the immunosuppressant.

Children under 18 (no safety studies in this age group).

Requires consultation with a doctor

Anticoagulant and antiplatelet medicines (warfarin, acenocoumarol, NOACs, clopidogrel, acetylsalicylic acid at cardiological doses). Tremella polysaccharides may prolong the partial thromboplastin time. The effect is mild, but alongside anticoagulant treatment it requires INR monitoring.

Antidiabetic medicines (insulin, metformin, sulfonylureas, incretins). Given the influence of β-glucans on metabolism described in the research, caution, glycaemic monitoring and a consultation with a diabetologist are advised alongside such treatment.

Pregnancy and breastfeeding. In TCM Tremella is traditionally considered safe in pregnancy, but there are no RCTs in this population. Caution is advised and use only after consultation.

Planned surgery: given a possible mild anticoagulant effect, stop Tremella at least 14 days before the procedure.

Possible side effects and safe serving

Reported rarely: gastrointestinal complaints (bloating, loose stools, a feeling of fullness) linked to the mucilaginous nature of the polysaccharides, more common in people with weak digestion (solution: halve the serving, take with a warm meal); allergic reactions in people hypersensitive to mushrooms; a mild feeling of coldness in the stomach on an empty stomach in people with a constitutionally cold digestion (solution: take with a warm drink or after a meal).

The cited RCTs (Ban 2018, Gitsomboon 2024) reported no side effects. Serving, timing and preparation are given on the current product label; do not convert amounts from scientific studies into a supplement serving yourself.

Honest about what is known

We also show what is not proven. This is a dietary supplement, not a medicine.

0

Strong evidence

confirmed composition

7

Preliminary

in vitro and animal studies

3

Not proven

no human studies

Reviewed by

Mateusz Rosa · Doctor of Acupuncture (WFAS)

Version 2.0 · Updated: 24 August 2026 · Subject-matter reviewer: Mateusz Rosa, founder of Aloha Fungi, TCM therapist, Doctor of Acupuncture (WFAS), author of books on functional mushroom supplementation.

Based on 11 verified sources

See sources

Strength of evidence: an honest qualification of claims

ClaimType of evidenceStrength
HbA1c and waist-circumference result in one study of a specific beverageRCT n=56, 12 wks, double-blind, p<0.05 (Gitsomboon 2024)PRELIMINARY
Cognitive results in one study of a specific preparationRCT n=75, 8 wks, double-blind, two doses (Ban 2018)PRELIMINARY
Water binding by TFPS polysaccharides in materials researchrepeatedly confirmed in vitro, review monographs (Wu 2019, Mendes 2025)PRELIMINARY
Tremella stimulates NGF synthesis by astrocytes and activates CREBin vitro PC12h and animal model (Park 2007, Park 2012), no human RCT measuring NGFPRELIMINARY
Support for synthesis of collagen I, elastin and endogenous HA in skinUVA-stimulated fibroblasts (Hu 2021), animal D-galactose ageing models (Wen 2016)PRELIMINARY
Tremella supports Lung Yin and mucous-membrane moistening in dry coughTCM tradition, small clinical studies, no large RCTsPRELIMINARY
Anti-stress action through HPA-axis modulation (uridine, mannose)animal model (Lee 2025), no human RCTPRELIMINARY
„Tremella erases wrinkles" or rejuvenates skin in humansno RCT with measured skin parametersNONE
„Cures" Alzheimer’s, dementia or MCInone, claim unsupported and prohibited by regulationNONE
„Tremella replaces hyaluronic acid in cosmetics"similar humectant mechanism, but different chemical compoundsNONE

STRONG = solid evidence · PRELIMINARY = moderate or preliminary · NONE = unsupported or prohibited by regulation.

Frequently asked questions

Is Tremella really better than hyaluronic acid?
There is no basis for that comparison. Hyaluronic acid is a glycosaminoglycan, while Tremella TFPS are polysaccharides with a different structure. Materials research describes similarities in selected water-binding properties, but there is no direct clinical comparison in humans.
Does oral Tremella replace a cream?
No clinical study establishes that an oral Tremella supplement replaces a cosmetic or changes measured skin parameters in humans. Choosing external skincare is a separate decision.
What serving of Tremella should I use?
Use the serving on the current label for the specific variant. Quantities from studies concerned other preparations and should not be converted into Aloha Fungi capsules, drops or powder without guidance. Do not exceed the recommended daily serving.
After how long will I notice an effect?
There is no reliable universal timeline for an effect. Available studies concerned specific preparations, participants and endpoints. They do not justify promising a change in skin, memory or wellbeing after a set period.
Can I combine Tremella with Reishi, Lion’s Mane, Cordyceps?
No clinical studies establish a particular benefit from these combinations. Check every product label, do not add servings together yourself and ask a clinician about the combination if you take medicines or remain under ongoing medical care.
Tremella or Lion’s Mane, which should I choose?
They are different raw materials, and no clinical study compares their products head to head. NGF data come mainly from cell and animal models, so they do not justify a promise of better memory or a recommendation to combine the products.
Does evening timing have a special role?
There is not enough clinical evidence to assign a particular benefit to evening timing. Descriptions of evening use belong to TCM tradition. In practice, follow the instructions on the label for the specific variant.
Why a fruiting-body extract rather than mycelium on grain?
A fruiting body and mycelium grown on grain are different raw materials. Instead of assuming superiority from the name alone, compare the part of the mushroom, carriers, extraction method, declared standardisation and a laboratory document matched to the batch number.

Scientific bibliography

  1. Gitsomboon S et al. (2024). Tremella fuciformis beverage improves glycated hemoglobin A1c and waist circumference in overweight/obese prediabetic subjects: a randomized controlled trial. BMC Nutr 10:43. PMID: 38439104.
  2. Ban S et al. (2018). Efficacy and Safety of Tremella fuciformis in Individuals with Subjective Cognitive Impairment: A Randomized Controlled Trial. J Med Food 21(4):400-407. PMID: 29319408.
  3. Wu YJ et al. (2019). Structure, bioactivities and applications of the polysaccharides from Tremella fuciformis mushroom: A review. Int J Biol Macromol 121:1005-1010. PMID: 31030755.
  4. Park KJ et al. (2007). The Neuroprotective and Neurotrophic Effects of Tremella fuciformis in PC12h cells. Mycobiology 35(1):11-15. PMID: 24015063.
  5. Park HJ et al. (2012). Tremella fuciformis enhances the neurite outgrowth of PC12 cells and restores trimethyltin-induced impairment of memory in rats via activation of CREB transcription and cholinergic systems. Behav Brain Res 229(1):82-90. PMID: 22227505.
  6. Fu H et al. (2021). Tremella fuciformis polysaccharides inhibit UVA-induced photodamage of human dermal fibroblast cells by activating up-regulating Nrf2/Keap1 pathways. J Cosmet Dermatol 21(9):4015-4024. PMID: 33686752.
  7. Wen L et al. (2016). Tremella fuciformis-derived polysaccharides protect d-galactose induced skin aging in mice. J Sci Food Agric 96(6):2110-2118.
  8. Shen T et al. (2017). Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1. Mol Med Rep 16(2):1340-1346. PMID: 28627707.
  9. Mendes M et al. (2025). Non-Animal Hyaluronic Acid from Tremella fuciformis: A New Source with a Structure and Chemical Profile Comparable to Hyaluronic Acid. Foods 14(8):1362.
  10. Moon G et al. (2025). Anti-Stress Effects of Tremella fuciformis Berk. Enzymatic Extracts: A Preclinical Study. Nutrients 17(5):914.
  11. Khamlue R et al. (2024). Recent advances in polysaccharides from Tremella fuciformis: isolation, structures, bioactivities and application. Front Pharmacol 15:1437534.

The educational content on this page does not replace medical advice. A dietary supplement is not a medicine and should not replace a varied diet or medical consultation. Before starting supplementation, especially with chronic conditions, pregnancy, breastfeeding or when taking medication, consult a doctor. Aloha Fungi does not claim therapeutic efficacy for any product; the mechanisms described are based on the current state of the literature. All products are dietary supplements notified to the Polish Chief Sanitary Inspectorate (GIS).

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